Mandal, Santanu and Ummadi, Raviteja and Bose, Madhuparna and Balla, V K and Roy, Mangal (2019) Fe-Mn-Cu alloy as biodegradable material with enhanced antimicrobial properties. Materials Letters, 237. pp. 323-327. ISSN 0167-577X
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Abstract
Degradable iron (Fe) based materials have been widely investigated for fracture fixation to overcome complications of permanent implants. Our study is focused on the development of a new Fe-Mn-Cu alloy with enhanced antimicrobial properties. In this work, Fe-Mn-Cu alloys, with up to 10 wt% copper (Cu), were prepared by powder metallurgy route. Degradation behaviour of the alloys were studied using potentiodynamic polarization test which showed nearly about 6 times increase in corrosion rate for 10 wt% Cu compared to the base alloy. Addition of Cu has significantly increased microhardness for up to 5 wt% and decreased thereafter. Broth micro-dilution test showed increased antimicrobial activity with Cu addition in Fe-Mn alloy while in vitro cytocompatibility study showed more than 70% cell viability for all alloys. Present study indicates that Cu alloying in Fe-Mn makes it a suitable material for internal fracture fixation devices with enhanced antimicrobial properties. (C) 2018 Elsevier B.V. All rights reserved.
Item Type: | Article |
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Subjects: | Engineering Materials |
Divisions: | UNSPECIFIED |
Depositing User: | Bidhan Chaudhuri |
Date Deposited: | 15 Nov 2019 07:43 |
Last Modified: | 15 Nov 2019 07:43 |
URI: | http://cgcri.csircentral.net/id/eprint/4624 |
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