Kundu, Biswanath and Sinha, Mithlesh Kumar and Basu, Debabrata (2002) Development of bio-active integrated ocular implant for anophthalmic human patients. Trends in Biomaterials and Artificial Organs, 16 (1). pp. 1-4. ISSN 0971-1198

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Abstract

Hydroxyapatite (HAp) powder was synthesized in the laboratory through wet chemical route and mixed with naphthalene powder in 1: 3 w/w ratio, which was homogenized, pressed iso-statically and subsequently turned to prepare samples of predetermined size and shape. They were finally sintered at 1200 – 13000 C for 4 hrs. and were tested for different physical, mechanical and tribological properties and used for clinical trials to establish non-toxicity and bio-compatibility. The material in granular form was introduced to Mongrel dogs and thereafter to human patients for bone-grafting operations and the results are discussed. Finally, out of these materials highly porous orbital implants of different designs have been prepared and after thorough sterilization they have been introduced to the Mongrel dog and subsequently to the anophthalmic human patients after enucleation / evisceration surgery. The results of the preliminary short-term clinical investigations are outlined and performances are compared with that of the conventional ones.

Item Type:	Article
Subjects:	Engineering Materials
Divisions:	Bioceramics & Coating
Depositing User:	Bidhan Chaudhuri
Date Deposited:	04 Dec 2012 12:58
Last Modified:	04 Dec 2012 12:58
URI:	http://cgcri.csircentral.net/id/eprint/1828

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